Periogen reduces dental plaque and tartar buildup with each application. Tartar is fossilized plaque and comprised primarily of calcium phosphate salt. The time required to remove your tartar varies depending upon age of tartar, the genetic predisposition for your body to produce tartar, and your commitment to the Periogen routine. In September of 2015 Periogen study results were presented at the premiere dental event, "The World Dental Congress." This was an exciting milestone for us and we wish to thank our long-time customers for their support and feedback which encouraged our determination and ability to initiate studies to prove what you experienced first-hand. Two independent studies were completed this year. One study was facilitated by a U.S. Dental University and the other by an International Dental University. The results from both studies prove that Periogen reduces plaque and tartar and fights Gingivitis. In the International study, patients had their teeth cleaned by a dental professional. Half of the group ("placebo group") brushed with a leading toothpaste while the other half brushed with the same toothpaste, but added swishing with Periogen to their routine. There was a statistically significant improvement in the patients swishing with Periogen. Periogen users realized a 45% reduction in plaque and tartar indexes as measured after 6 months of Periogen use as compared to brushing alone. (Published Data: Int J Experiment Dent Sci 2015;4(1):33-39) If you have any questions or comments please contact us through our website.