Faecal calprotectin is a substance that is released into the intestines in excess when there is any inflammation there. Its presence can mean a person has an inflammatory bowel disease such as Crohn's disease or ulcerative colitis. Inflammatory bowel diseases are considered autoimmune diseases, in which the body's own immune system attacks elements of the digestive system. Both Crohn's disease and ulcerative colitis are chronic (long-term) diseases that involve inflammation of the gastrointestinal tract (gut). However, there are important differences between the two. Ulcerative colitis only affects the colon (large intestine), while Crohn's disease can affect the entire digestive system, from the mouth to the anus. These conditions can cause very similar symptoms to irritable bowel syndrome. But, Crohn's disease and ulcerative colitis can also cause symptoms serious enough for major surgery to be needed, so it's important to distinguish between them and irritable bowel syndrome. Many people with irritable bowel syndrome have unnecessary invasive hospital investigations before their condition is diagnosed. Using faecal calprotectin testing will mean most people with irritable bowel syndrome will be diagnosed without the need for these investigations. Pack contents include all items required to obtain and effect a result from which further medical diagnosis/treatment can be determined. This test is fully CE approved for medical/professional use. If any positive result is obtained it is important the patient seek immediate medical advice.