What is IP-6? IP-6 (inositol hexaphosphate) is a component of certain dietary fibers, particularly most cereal grains, legumes, and seeds high in oil. Many researchers believe some of fiber's health benefits may be due to the antioxidant, immune-enhancing, and cardiovascular-supporting activities of IP-6. IP-6 is one form of inositol. Inositol is a kind of sugar formed by 6 carbon atoms, 6 oxygen atoms, and 12 hydrogen atoms. This combination of atoms can also form glucose, but the atoms are arranged differently in these 2 sugars. There are actually several forms of inositol, each with subtle differences in the arrangement of atoms, with myo-inositol being the most common form. IP-6 is formed by substituting phosphate groups (each with a phosphorous and three oxygens) for each of the 6 hydroxyl (an oxygen and hydrogen) groups of inositol. Thus, IP-6 is related, yet chemically distinct, from myo-inositol, which is being studied for its possible role in illnesses such as depression and anxiety. What does IP-6 do? In-vitro and animal research has shown IP-6 to have significant protective and growth-regulating effects on various cells and tissues including those of the colon, breast, and prostate. Proponents call IP-6 a "natural cancer fighter" and claim it slows or reverses the growth of various forms of cancer, including breast, colon, and prostate cancers. It is thought to be an antioxidant, a compound that blocks the action of free radicals, activated oxygen molecules that can damage cells. It may help to prevent the abnormal signals that tell a cancer cell to keep growing from reaching the cell's nucleus. Some research shows IP-6 slows abnormal cell division and may sometimes transform tumor cells into normal cells. Supporters also claim it effectively prevents kidney stones, high cholesterol, heart disease, and liver disease. IP-6 is converted into compounds in the body that are used by cells to relay outside messages to the cell nucleus.